研究業績

2017年

  1. Masahiro Uchibori, Ken-ichi Aoyama, Yoshihide Ota, Kagemasa Kajiwara, Masafumi Tanaka, Minoru Kimura: A mutation in NOTCH1 ligand binding region detected in patients with oral squamous cell carcinoma reduces NOTCH1 oncogenic effect. Oncology Reports (2017) 38(4) 2237-2242 Oct.
  2. Hitoshi Endo, Tomoo Eto , Fumihito Yoshii , Satoshi Owada , Tetsu Watanabe , Masayuki Tatemichi , Minoru Kimura:  The intrauterine environment affects learning ability of Tokai high avoider rat offspring derived using cryopreservation and embryo transfer-mediated reproduction. Biochem. Biophys. Res Comm. (2017) 489(2), 211-216 July
  3. Ganesh Kumar Mani, Kousei Miyakoda, Asuka Saito, Yutaka Yasoda, Kagemasa Kajiwara, Minoru Kimura, and Kazuyoshi Tsuchiya Microneedle pH Sensor: Direct, Label-free, Real Time Detection of Cerebrospinal Fluid and Bladder pH: ACS Appl. Mater. Interfaces, Just Accepted Manuscript • Publication Date (Web): 06 Jun 2017
  4. Hisako Akatsuka; Shuhei Kuga; Kaori Masuhara; Odontuya Davaadorj; Chisa Okada; Yumi Iida; Yoshinori Okada; Nahoko Fukunishi; Takahiro Suzuki; Kazuyoshi Hosomichi; Masato Ohtsuka; Masafumi Tanaka; Ituro Inoue; Minoru Kimura; AMBRA1 is involved in T cell receptor-mediated metabolic reprogramming through an ATG7-independent pathway. Biochem. Biophys. Res Comm. (2017)  Sep 30;491(4):1098-1104. doi: 10.1016/j.bbrc.2017.08.019. Epub 2017 Aug 5
  5. Mani, G.K., Miyakado, K., Saito, A., Yasoda, Y., Kajiwara, K., Kimura, M. and Tsuchiya, K.: Microneedle pH sensor; Direct, Label-Free, Real-Time Detection of Cerebrospinal Fluid and Bladder pH. ACS applied materials & interfaces 9, (26) 21651-21659 (2017) July

2016

  1. Shin-ichiro Mugikura, Akira Katoh, Satoshi Watanabe, Minoru Kimura and Kagemasa Kajiwara Abnormal gait, reduced locomotor activity and impaired motor coordination in Dgcr2-deficient mice. Biochem. Biophys. Rep. 5, 120-126 (2016) http://dx.doi.org/10.1016/j.bbrep.2015.11.015 (2015)
  2. Makoto Arai, Yoshinobu Nakada, Kagemasa Kajiwara, Minoru Kimura and Naoaki Ishii Preparation of sennnoside-reduced rhubarb. Tokai J. Exp. Clin. Med. (2016) Mar. 20; 41(1)24-29
  3. Shingo Suzuki1, Takehito Sato2, Hisako Akatsuka1,2, Minoru Kimura1 and TakashiShiina1: Identification of a novel HLA-C allele, HLA-C*03:313, in a Japanese individual. HLA(Tissue Antigen) (2016) Mar;87(3):186-7. doi: 10.1111/tan.12750. Epub 2016 Feb 22. 2.137
  4. Sakabe, K., Kimura, M., Terayama, H., Tsunoda, M., Miyajima, E., Takano, H., Azuma, K., Mizukoshi, A., Matsuda, T., Mori, C., Kawakami, S., Miyata, M., Ishikawa, S. and Aizawa, Y. : Chemical Sensitivity-The Frontier of Diagnosis and Treatment (2016) Review Japanese Journal of Clinical Oncology 臨床環境医学Dec. 31 25(2), 49-54

2015

  1. Furukawa, S., Kuwajima, Y., Chosa, N., Satoh, K., Ohtsuka, M., Hiromi Miura, Minoru Kimura, Hidetoshi Inoko, Akira Ishisaki, Akira Fujimura, Hiroyuki Miura: Establishment of immortalized mesenchymal stem cells derived from the submandibular glands of tdTomato transgenic mice. Experimental and Therapeutic Medicine (2015) Oct;10(4):1380-1386. Epub 2015 Aug 24.
  2. Ohtsuka, M ., Miura, H., Mochida, K., Hirose, M., Hasegawa, A., Ogura, A., Mizutani, R., Kimura, M., Isotani, A., Ikawa, M., Sato, M. and Gurumurthy, CB : One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT). BMC Genomics. 2015 Apr 9;16:274. doi: 10.1186/s12864-015-1432-5 3.986
  3. Miura, H., Inoko, H., Tanaka, M., Nakaoka, H., Kimura, M., Gurumurthy, CB, Sato, M. and Ohtsuka, M. : Assessment of artificial miRNA architectures for higher knockdown efficiencies without the undesired effects in mice. PLoS One (2015) Aug.18; 10(8) e0135919. 3.234
  4. Takehito Sato, Hisako Akatsuka, Yoshiki Yamaguchi, Kyoko Miyashita, Masafumi Tanaka, Tetsuro Tamaki, Masato Ohtsuka, Minoru Kimura: Establishment of -2 microglobulin deficient human iPS cells using CRISPR/Cas9 system. (in press) Integrative Molecular Medicine (2015) doi: 10.15761/IMM.1000171 Volume 2(6): 373-377

2014

  1. Tsuchiya, K., Saidin, MYB., Inoue, T., Kajiwara, K and Kimura, M. Qualitative measurement of pain by analyzing the salivary alpha amylase. Precision Engineering. 38 257-260 (2014) 1.517
  2. Tsuchiya, K., Iimori, S., Kajiwara, K. and Kimura, M. Interaction between carbon nanotubes and human cell. Precision Engineering. 38, 116-120 (2013) 1.517
  3. Ken-ichi Aoyama; Yoshihide Ota, Kagemasa Kajiwara, Noriaki Hirayama,and Minoru Kimura: Frequent mutations in NOTCH1 ligand-binding regions in Japanese oral squamous cell carcinoma. Biochemical and Biophysical Research Communications (2014) Oct 3;452(4):980-5. doi: 10.1016/j.bbrc. 2014.09.021. Epub 2014 Sep 16. 2.297
  4. Watanabe, S., Haraguchi, S., Nakamura, S., Sakurai, T., Mugikura, S. Kajiwara, Kimura M. and Sato, M. Novel cancer vaccination system based on human endo-ß-N-acetyl glucosaminidase gene delivery. J Glycobiol 3 (1), 106, 2014 http://dx.doi.org/10.4172/2168-958X.1000106

2013

  1. Matsuzaka, Y., Ohkubo, T., Yukie Y. Kikuti, Mizutani A., Tsuda, M., Aoyama, Y., Kakuta, K., Oka, A., Inoko, H., Sakabe, K., Ishikawa, S., Kulski, JK. and Kimura, M. Association of sick building syndrome with neuropathy target esterase (NTE) activity in Japanese. Environmental Toxicology Jun;65(6):405-415 (2013) 2013 Feb 18. doi: 10.1002/tox.21839. [Epub ahead of print]
  2. Chiba, T., Inoko, H., Kimura, M. and Sato, T. Role of nuclear IκBs in inflammation regulation. BioMolecular Concepts (2013) Apr.4(2):187-196 doi:10.1515/bmc-2012-0039
  3. Mitsunaga, S., Shimizu, S., Okudaira, Y., Oka., A., Tanaka, M., Kimura, M., Kulski, J.K. Inoue, I. and Inoko H. Improved loop-mediated isothermal amplification for HLA-DRB1 genotyping using RecA and a restriction enzyme for enhanced amplification specificity Immunogenetics (2013) Jun;65(6):405-15. doi: 10.1007/s00251-013-0690-0. Epub 2013 Mar 9.2.227
  4. Ohtsuka, M., Miura, H., Hayashi, H., Nakaoka, H., Kimura, M., Sato, M. and Gurumurthy , CB: Improvement of pronuclear injection-based targeted transgenesis (PITT) by iCre mRNA-mediated site-specific recombination Transgenic Research (2013) Aug.;22(4):873-5. doi: 10.1007/s11248-013-9703-x. Epub 2013 Mar 26 2.322
  5. Mizutani,  R., Taguchi, K., Ohtsuka, M., Kimura, M., Takeuchi, A., Uesugi, K. and Suzuki, Y.: X-ray microtomographic visualization of Escherichia coli by metalloprotein overexpression Journal of Synchrotron Radiation (2013) 20, 581-586 2.794

2012

  1. Matsuzaka, Y., Kikuti, YY., Izumi, D., Goya, K., Suzuki, T., Cai, L., Oka, A., Inoko, H. Kulski, JK.,and KimuraM. Failure in detection of significant association between estrogen receptor-alpha gene polymorphisms and endometriosis in Japanese women. Environmental Health and Preventive Medicine 17(5), 423-428 (2012)
  2. Matsuzaka, Y., Kikuti, YY., Izumi, S., Goya, K., Suzuki, T., Cai, L., Oka, A., Inoko, H., Kulski , JK and Kimura M. Lack of an association human dioxin detoxification genes polymorphisms with endometriosis in Japanese women: results of a pilot study. Environmental Health and Preventive Medicine 17(6): 512-517 DOI: 10.1007/s12199-012-0281-y (2012)
  3. Ohtsuka, M., Miura H., Gurunurthy, C.B., Kimura, M., Inoko H., Yoshimura, S. and Sato, M. Fluorescent transgenic mice suitable for multi-color aggregation chimera studies. Cell Tissue Res. 2012 Nov;350(2):251-60. doi: 10.1007/s00441-012-1470-0. Epub 2012 Aug 7. 3.565
  4. Ohtsuka, M., Miura, H., Sato, M., Kimura, M., Inoko H., Gurumurthy, CB. PITT: Pronuclear Injection-Based Targeted Transgenesis, a Reliable Transgene Expression Method in Mice . Exp Anim. 61(5):489-502. Review (2012) 0.965